Sodium accumulation during ischemia induces mitochondrial damage in perfused rat hearts
نویسندگان
چکیده
منابع مشابه
Sodium accumulation during ischemia induces mitochondrial damage in perfused rat hearts.
OBJECTIVE The present study aimed to elucidate the involvement of sodium overload and following damage to mitochondria during ischemia in the genesis of ischemia/reperfusion injury of perfused rat hearts. METHODS Isolated, perfused hearts were exposed to different durations (15-35 min) of ischemia followed by 60-min reperfusion. At the end of ischemia or reperfusion, myocardial sodium and cal...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2002
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(02)00282-1